BPC-157
Recovery & tissue support
Tendons, ligaments, and gut lining healed significantly faster in animal models given BPC-157 versus controls, across 100+ published studies.
Curr Pharm Des, 2013
Read the study ↗Tendon cells treated with BPC-157 produced 2x more growth hormone receptors — the mechanism behind faster connective tissue repair in animal studies.
Molecules, 2014
Read the study ↗Damaged stomach and intestinal lining showed accelerated recovery in animal models. Researchers noted protective effects on gut barrier integrity.
Curr Pharm Des, 2018
Read the study ↗Size
Quantity
Purchase frequency
In stock · Ships within 24 hours
Third-party
tested
Free shipping
over $75
COA
included
Reconstitution: Add 2mL bacteriostatic water per 5mg vial (2.5mg/mL). Reconstituted solution should be stored at 2-8°C and used within 30 days. Unreconstituted vials: -20°C. Refer to your institutional protocol for specific preparation requirements.
For laboratory research use only. Not for human consumption.
Purity
≥98%
Molecular weight
1419.53 g/mol
Form
Lyophilized powder
Storage
Store at -20°C. Protect from light and moisture.
Amino acid sequence
Tendons, ligaments, and gut lining healed significantly faster in animal models given BPC-157 versus controls, across 100+ published studies.
Sikiric P, et al. — Curr Pharm Des, 2013↗
Tendon cells treated with BPC-157 produced 2x more growth hormone receptors — the mechanism behind faster connective tissue repair in animal studies.
Chang CH, et al. — Molecules, 2014↗
Damaged stomach and intestinal lining showed accelerated recovery in animal models. Researchers noted protective effects on gut barrier integrity.
Sikiric P, et al. — Curr Pharm Des, 2018↗
Independent lab results — HPLC purity and mass spectrometry identity confirmation.
Download COA (PDF) ↗HPLC purity verified
Mass spec ID confirmed
Batch-specific COA
Published COA before purchase
PubMed citations on PDP
What purity level is this?
Every batch is verified at ≥98% purity via HPLC analysis by an independent laboratory. The COA for your specific batch is available on this page.
What is the difference between 5mg and 10mg?
The peptide is identical. The 10mg vial contains twice the quantity at a lower per-mg cost ($6.90/mg vs $7.80/mg).
How should I store this?
Unreconstituted: -20°C freezer, protected from light. Reconstituted: 2-8°C refrigerator, use within 30 days.
Tendons, ligaments, and gut lining healed significantly faster in animal models given BPC-157 versus controls, across 100+ published studies.
Curr Pharm Des, 2013
Read the study ↗Tendon cells treated with BPC-157 produced 2x more growth hormone receptors — the mechanism behind faster connective tissue repair in animal studies.
Molecules, 2014
Read the study ↗Damaged stomach and intestinal lining showed accelerated recovery in animal models. Researchers noted protective effects on gut barrier integrity.
Curr Pharm Des, 2018
Read the study ↗BPC-157
Recovery & tissue support
Size
Quantity
Purchase frequency
In stock · Ships within 24 hours
Third-party
tested
Free shipping
over $75
COA
included
Reconstitution: Add 2mL bacteriostatic water per 5mg vial (2.5mg/mL). Reconstituted solution should be stored at 2-8°C and used within 30 days. Unreconstituted vials: -20°C. Refer to your institutional protocol for specific preparation requirements.
For laboratory research use only. Not for human consumption.
Purity
≥98%
Molecular weight
1419.53 g/mol
Form
Lyophilized powder
Storage
Store at -20°C. Protect from light and moisture.
Amino acid sequence
Tendons, ligaments, and gut lining healed significantly faster in animal models given BPC-157 versus controls, across 100+ published studies.
Sikiric P, et al. — Curr Pharm Des, 2013↗
Tendon cells treated with BPC-157 produced 2x more growth hormone receptors — the mechanism behind faster connective tissue repair in animal studies.
Chang CH, et al. — Molecules, 2014↗
Damaged stomach and intestinal lining showed accelerated recovery in animal models. Researchers noted protective effects on gut barrier integrity.
Sikiric P, et al. — Curr Pharm Des, 2018↗
Independent lab results — HPLC purity and mass spectrometry identity confirmation.
Download COA (PDF) ↗HPLC purity verified
Mass spec ID confirmed
Batch-specific COA
Published COA before purchase
PubMed citations on PDP
What purity level is this?
Every batch is verified at ≥98% purity via HPLC analysis by an independent laboratory. The COA for your specific batch is available on this page.
What is the difference between 5mg and 10mg?
The peptide is identical. The 10mg vial contains twice the quantity at a lower per-mg cost ($6.90/mg vs $7.80/mg).
How should I store this?
Unreconstituted: -20°C freezer, protected from light. Reconstituted: 2-8°C refrigerator, use within 30 days.
BPC-157
Key Benefits
Tissue models
Studied for accelerated tendon and ligament repair in animal models.
Gut lining
Research shows protective effects on gastrointestinal epithelial cells.
Connective tissue
Upregulates growth hormone receptors in tendon-derived fibroblasts.
Well-studied
Over 100 published studies across multiple preclinical models.
Peer-reviewed research
Top Published Studies
Curr Pharm Des
2013
Stable gastric pentadecapeptide BPC 157 in trials for i...
Sikiric P, et al.
"Tendons, ligaments, and gut lining healed significantly faster in animal models given BPC-157 versus controls, across 100+ published studies."
Molecules
2014
Pentadecapeptide BPC 157 enhances the growth hormone re...
Chang CH, et al.
"Tendon cells treated with BPC-157 produced 2x more growth hormone receptors — the mechanism behind faster connective tissue repair in animal studies."
Curr Pharm Des
2018
BPC 157 and the gastrointestinal tract
Sikiric P, et al.
"Damaged stomach and intestinal lining showed accelerated recovery in animal models. Researchers noted protective effects on gut barrier integrity."
These citations are from peer-reviewed journals. Sequence does not make therapeutic claims.
Peptide science
How It Works
Step 1
Receptor binding
BPC-157 binds to specific cell surface receptors, triggering a defined downstream signaling cascade. Each peptide targets a unique receptor profile.
Step 2
Signal activation
The receptor interaction activates intracellular pathways that regulate gene expression, protein synthesis, and cellular behavior in the target tissue.
Step 3
Biological response
BPC-157 is a 15-amino-acid peptide fragment derived from gastric juice. In preclinical models, it has been shown to upregulate growth hormone receptor expression in tendon cells, promote angiogenesis at injury sites, and accelerate epithelial cell migration. Its mechanism involves multiple pathways including the NO system, FAK-paxillin, and the GH receptor axis.
Community sentiment
4.8
5 discussions
From r/Peptides and r/Nootropics
Community discussions. Not endorsed by Sequence. Individual experiences do not constitute research evidence.
BPC-157 is probably the most well-studied peptide out there. I've seen the Sikiric papers — over 100 studies on this compound. The consistency of results across different tissue models is what stands out.
Ran BPC-157 for my shoulder. 250mcg 2x daily subq near the site. By week 3 the improvement was noticeable. By week 5 I had full ROM back. Your mileage may vary obviously.
What I like about BPC is the safety profile in the literature. No reported serious adverse effects across all the animal studies. That's rare for any compound.